FLUNIXAMINE

FLUNIXAMINE

BEEF: For control of fever caused by BRD

• FLUNIXAMINE^® (flunixin meglumine) Injectable Solution is indicated for the control of pyrexia associated with bovine respiratory disease (BRD).

DAIRY: For control of pyrexia due to mastitis

• FLUNIXAMINE is indicated for the control of pyrexia associated with endotoxemia and acute bovine mastitis. It also is indicated for the control of inflammation in endotoxemia.

HORSES: For pain relief

• FLUNIXAMINE is recommended for the alleviation of inflammation and pain associated with musculoskeletal disorders. It also is recommended for the alleviation of visceral pain associated with colic.
• Dosing & Administration

  Horse: The recommended dose for musculoskeletal disorders is 0.5 mg per pound (1 mL/100 lbs.) of body weight once daily. Treatment may be given by intravenous or intramuscular injection and repeated for up to 5 days. Studies show onset of activity is within 2 hours. Peak response occurs between 12 and 16 hours and duration of activity is 24 to 36 hours.

  The recommended dose for the alleviation of pain associated with equine colic is 0.5 mg per pound of body weight. Intravenous administration is recommended for prompt relief. Clinical studies show pain is alleviated in less than 15 minutes in many cases. Treatment may be repeated when signs of colic recur. During clinical studies approximately 10% of the horses required one or two additional treatments. The cause of colic should be determined and treated with concomitant therapy.

  Cattle: The recommended dose for control of pyrexia associated with bovine respiratory disease and endotoxemia and control of inflammation in endotoxemia is 1.1 to 2.2 mg/kg (0.5 to 1.0 mg/lb.; 1 to 2 mL per 100 lbs.) of body weight given by slow intravenous administration either once a day as a single dose or divided into two doses administered at 12-hour intervals for up to 3 days. The total daily dose should not exceed 2.2 mg/kg (1.0 mg/lb.) of body weight. Avoid rapid intravenous administration of the drug.

  The recommended dose for acute bovine mastitis is 2.2 mg/kg (1 mg/lb.; 2 mL per 100 lbs.) of body weight given once by intravenous administration.

  IMPORTANT SAFETY INFORMATION: FLUNIXAMINE has a four day pre-slaughter withdrawal time. Milk that has been taken during treatment and for 36 hours after the last treatment must not be used for food.  Not for use in dry dairy cows. Do not use in calves to be processed for veal. Do not use in bulls intended for breeding. NSAIDS are known to have potential effects on both parturition and estrus cycle. Intramuscular administration has resulted in illegal residues. Do not use in horses intended for food.

  Cattle
  IMPORTANT SAFETY INFORMATION: FLUNIXAMINE has a four day pre-slaughter withdrawal time. Milk that has been taken during treatment and for 36 hours after the last treatment must not be used for food.  Not for use in dry dairy cows. Do not use in calves to be processed for veal. Do not use in bulls intended for breeding. NSAIDS are known to have potential effects on both parturition and estrus cycle. Intramuscular administration has resulted in illegal residues.

  Equine
  IMPORTANT SAFETY INFORMATION: Do not use FLUNIXAMINE in horses intended for food. NSAIDS are known to have potential effects on both parturition and estrus cycle. Drug compatibility should be monitored closely in patients requiring adjunctive therapy.