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HomeInjectable ETAPHYLLINE
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ETAPHYLLINE

$70.00 $65.00

ETAPHYLLINE is a drug called xanthine bronchodilators. Other related drugs include theobromine and caffeine. These drugs have a number of pharmacologic effects including relaxation of bronchial smooth muscle, bronchial anti-inflammatory actions, central nervous system stimulation, mild diuresis, increased gastric acid secretion and mild cardiac stimulation.

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Category: Injectable Tags: #buy ETAPHYLLINE, #buy ETAPHYLLINEonline, #ETAPHYLLINE online, ASTHMA, BRONCHODILATORS, METHYL XANTHINES, PIPERAZINE, RESPIRATORY TRACT AGENTS
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Description

ETAPHYLLINE is a drug called xanthine bronchodilators. Other related drugs include theobromine and caffeine. These drugs have a number of pharmacologic effects including relaxation of bronchial smooth muscle, bronchial anti-inflammatory actions, central nervous system stimulation, mild diuresis, increased gastric acid secretion and mild cardiac stimulation. The mechanism of action is through the inhibition of phosphodiesterase which increases cyclic-AMP and endogenous epinephrine. Increased levels of c-AMP may also decrease histamine release. The respiratory anti-inflammatory effects of theophylline may occur at a lower dose than that needed for bronchial smooth muscle relaxation.

ETAPHYLLINE is well absorbed orally and is metabolized by the liver.

Dogs and Cats

ETAPHYLLINE is used as a bronchodilator in both dogs and cats to treat bronchoconstriction and inflammation associated with chronic inflammatory lower airway disease and feline asthma. Bronchodilators such as theophylline may be used with corticosteroids, and the use of a bronchodilator may permit a lowering of the dose of the corticosteroids. Theophylline is also used to treat both dogs and cats with collapsing trachea, intrathoracic airway collapse and pulmonary edema.

Side Effects

  • The most common side effects are central nervous system stimulation and gastrointestinal upset; particularly nausea and vomiting. Many of the milder side effects occur at the start of therapy but will resolve over time.
  • Some clinicians will start an animal on a lower dose and increase the theophylline to the therapeutic dose after the first week.
  • The less common and more serious side effects include cardiac stimulation and seizures.

Precautions

  • ETAPHYLLINE should be used with additional caution in animals with severe cardiac, renal or hepatic disease. It should also be used with additional caution in animals with seizure disorders, gastric ulcers, hyperthyroidism, hypertension, and severe hypoxia.
  • Neonates and geriatric patients may have increased clearance time, and may need additional monitoring. Animals with pre-existing cardiac arrhythmias or congestive heart failure may need additional monitoring.
  • ETAPHYLLINE has a low volume of distribution. The dose should be calculated based on lean body mass.
  • ETAPHYLLINE crosses the placenta. Approximately 70% of serum levels are found in milk. It should only be used in pregnant or nursing animals when the possible benefits outweigh the risks. crosses the placenta and has some anti-androgen properties in humans. It should only be used in pregnant or nursing animals when the benefits outweigh the risks due to the potential for feminization of fetuses. Spironolactone is found in maternal milk.

Drug Interactions

  • ETAPHYLLINE is metabolized by cytochrome P-450 enzymes of the liver. Other drugs that are metabolized by this enzyme system may interact with theophylline.
  • Drugs that inhibit the metabolism of and therefore increase levels of theophylline include: allopurinol, beta-blockers, propanolol, cimetidine, calcium channel blockers, corticosteroids, thiabendazole, exogenous thyroid hormone, macrolide antibiotics and flouroquinolone antibiotics.
  • Drugs that may increase the metabolism of and decrease levels of theophylline include: barbiturates, rifampin, carbamazine, charcoal, phenytoin, ketoconazole, and beta-agonists.
  • ETAPHYLLINE decreases the effects of lithium, pancuronium, and propofol.
  • Drugs that may either increase or decrease the levels of theophylline include: isoniazid and furosemide.
  • Concurrent use with ephedrine, isoproterenol, and halothane may increase the risk of cardiac side effects.
  • Concurrent use of theophylline with ketamine may increase the risk of seizures.

Overdose

  • Overdose may cause central nervous system stimulation including seizures and hyperthermia, life threatening tachycardia, and dysrhythmias.
  • If an oral overdose is recognized promptly, gut emptying protocols may be of benefit. Other treatments include activated charcoal, saline cathartics, fluid therapy, and supportive measures for shock.https://kihorsemed.com/
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DUPHALYTER Electrolyte, Energy substance, Amino Acid and Vitamin in solution for injection Laboratorio PFIZER, SA. Pharmaceutical form: Solution for injection (Sol.i.) Composition per ml: Calcium chloride (dihydrate) 0.23 mg; magnesium sulfate (heptahydrate) 0.29 mg; potassium chloride 0.20 mg .; dextrose 45.46 mg; arginine (hydrochloride) 25 ƒÊg; cysteine ​​(hydrochloride monohydrate) 0.01 mg; Phenylalanine 0.03 mg; glutamic acid (sodium salt monohydrate) 0.04 mg; histidine (hydrochloride monohydrate) 0.01 mg;isoleucine 0.01 mg; leucine 0.04 mg; lysine (hydrochloride) 0.03 mg; methionine 0.01 mg; threonine 0.02 mg; tryptophan 0.01 mg; valine 0.05 mg; cyanocobalamin 0.05 ƒÊg; dexpanthenol 0.05 mg; nicotinamide 1.50 mg; pyridoxine hydrochloride 0.10 mg;riboflavin 0.04 mg; thiamine 0.10 mg. Pharmacological properties General characteristics: The product provides a correct balance between water, minerals, vitamins and amino acids, in those animals lacking any of these compounds. Interactions and incompatibilities: None known. Indications and target species: Birds: Dehydration and convalescence. Pigs, Bovine and Equine: Dehydration, anorexia, bacterial enteritis and convalescence. Dogs and Cats: Dehydration, anorexia, bacterial enteritis, vomiting and convalescence. Product, in general, also recommended as support therapy in animals weakened by electrolyte imbalance and hypoproteinemia; in cases of incompetence, surgical operations, hemorrhages, excessive sweating, vascular shocks, exhaustion, weight loss, fever, inflammation of the digestive tract, and before transport, in all pets. Contraindications: None known. Side effects: Intravenous administration too quickly can cause nausea, vomiting and general malaise. If this happened, it would be enough to interrupt the application until the animal returned to its normal state and then continue the administration at a lower speed. Intravenous administration route slow, intraperitoneal or subcutaneous. – Slow intravenous: pigs, cattle, horses, dogs and cats. – Intraperitoneal: pigs and cattle. – Subcutaneous: birds (at the back of the neck), pigs, cattle, dogs and cats. It is recommended to use sterile syringes and inject the preparation at body temperature. Dosage: Poultry: 10 ml / kg pv In 1-day-old chicks: 0.5 ml / chick. Pigs, Cattle and Equine: Adult animal: 20 ml / 10 kg pv Young animal: 60 ml / 10 kg pv Dogs and Cats: 10 ml / kg pv Administration may be repeated as many times as necessary. Waiting time: Not accurate. Conservation mode Store in a cool, dry place and protected from light. Observations: With veterinary prescription. Presentation Bottles with 500 ml.
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